Fas ligand (FasL) Apoptosis

Circulating Plasma Gelsolin: A Predictor of Favorable Clinical Outcomes in Head and Neck Cancer and Sensitive Biomarker for Early Disease Diagnosis Combined with Soluble Fas Ligand

Head and neck most cancers (HNC) accounts for greater than 330,000 most cancers deaths yearly worldwide. Regardless of late prognosis being a significant factor contributing to HNC mortality, no passable biomarkers exist for early illness detection. Cytoplasmic gelsolin (cGSN) was found to foretell illness development in HNC and different malignancies, and circulating plasma gelsolin (pGSN) ranges are considerably correlated with infectious and inflammatory illness prognoses.

Right here, the plasma ranges of 5 candidate biomarkers (circulating pGSN, squamous cell carcinoma antigen, cytokeratin 19 fragment, soluble Fas, and soluble Fas ligand (sFasL)) in 202 sufferers with HNC and 45 wholesome controls have been measured utilizing enzyme-linked immunosorbent assay or Millipore most cancers multiplex assay. The outcomes demonstrated that circulating pGSN ranges have been considerably decrease in sufferers with HNC than in wholesome controls.

Furthermore, circulating pGSN outperformed different candidate biomarkers as an unbiased diagnostic biomarker of HNC in each sensitivity (82.7%) and specificity (95.6%). Receiver working attribute curves indicated that mixed pGSN and sFasL ranges additional augmented this sensitivity (90.6%) for early illness detection.  In conclusion, circulating pGSN might be an unbiased predictor of favorable scientific outcomes and a novel biomarker for the early HNC detection together with sFasL. sFas, sFasL and BAFF have been detectable in all samples.

Serum sFas and sFasL have been considerably greater in SLE in contrast with HC. In univariable regression analyses, sufferers with energetic renal illness and people with flare had considerably greater ranges of sFas in contrast with these with out. Excessive serum BAFF in sufferers with SLE was related to elevated sFas however not sFasL. The affiliation between sFas and renal illness remained important after adjusting for BAFF, however the affiliation with flare attenuated.

Excessive sFas ranges have been related to elevated time-adjusted imply SLEDAI-2K, even after adjusting for BAFF, and with greater odds of flare over time. In distinction, excessive sFasL was related to diminished organ injury over time. Serum sFasL/sFas ratio was negatively related to energetic general illness, flare and organ injury. Furthermore, greater pGSN ranges predicted improved prognosis at each 5-year general survival and progression-free survival.

Fas Ligand (FasL) in Affiliation with Tumor-Infiltrating Lymphocytes (TILs) in Early Stage Cervical Most cancers.

Thus far, little is understood in regards to the roles of FasL and TILs in cervical most cancers. This research goals to find out the correlation between FasL expression and TILs presence in cervical most cancers.On this research, we analysed the FasL and TIL presence in 32 squamous cell carcinoma or adenocarcinoma that have been obtained from early stage (≤ IIA2) cervical most cancers sufferers utilizing immunohistochemistry. The extent of FasL and TIL was assessed qualitatively, after which quantified with the H-Rating system.

Many of the sufferers have been between 30 to 50 years outdated (59,4%), and had by no means taken pap smear examination earlier than (96,9%). Primarily based on the Pearson evaluation of FasL and TIL presence, we discovered that FasL was inversely correlated with CD45 or TIL quantity when the extent of FasL is above 140 and the CD45 is under 160. Primarily based on Chi-Sq. check of FasL and TIL classification, there was a nine-fold odds ratio (OR) of decrease TILs classification in excessive expression of FasL classification (OR 9, p=0.01).

An inverse correlation between FasL expression and TILs degree, that may point out FasL-induced TILs apoptosis in tumor tissue, was noticed. The sturdy inverse correlation between FasL and TILs presence confirmed some perception in regards to the interactions between most cancers cells and its environment inside the cervical most cancers tissue. This may also be additional developed to tailor a prognostic marker that may predict the end result of remedy in sufferers, not solely in cervical most cancers, however typically in all most cancers.

Lengthy noncoding RNA LINC00324 exerts protumorigenic results on liver most cancers stem cells by upregulating fas ligand by way of PU field binding protein.

Hepatocellular carcinoma (HCC) represents a significant explanation for most cancers demise, however the molecular mechanism for its improvement has not but been properly characterised. Lengthy noncoding RNAs (lncRNAs) are concerned in a variety of organic processes by way of their roles as oncogenes or tumor suppressor genes. The current research aimed to elucidate the position of LINC00324 in HCC by means of its interplay with Fas ligand (FasL). Initially, microarray-based gene expression profiling of HCC was employed to determine differentially expressed genes.

Subsequent, the expression of LINC00324 in HCC tissues and liver most cancers stem cell (LCSC) strains was examined utilizing RT-qPCR. Then, the interplay amongst LINC00324, PU field binding protein (PU.1) and FasL was recognized with RIP, ChIP and dual-luciferase reporter gene assays. The impact of LINC00324 on viability, proliferation, migration, invasion, and apoptosis in addition to the tumorigenesis of transfected cells was examined with gain- and loss-of-function experiments. LINC00324 and FasL have been extremely expressed in HCC. LINC00324 regulated FasL expression by way of interplay with PU.1.

Flt-3 Ligand (CHO-expressed), Human
HY-P7111	MedChemExpress	100ug	EUR 946

rHu FLT-3-Ligand (cGMP)
AK9805-0000	Akron Biotech	1mg	Ask for price

flt-3-Ligand, murine recombinant
4086-10	Biovision		EUR 245

flt-3-Ligand, murine recombinant
4086-1000	Biovision		EUR 4128

flt-3-Ligand, murine recombinant
4086-50	Biovision		EUR 697

Flt-3 Ligand Recombinant Protein
11-374	ProSci	0.1 mg	EUR 595.25
Description: FMS-like tyrosine kinase 3 ligand (Flt-3 Ligand) is also known as FL, Flt3L and FLT3LG, is an α-helical cytokine that promotes the differentiation of multiple hematopoietic cell lineages. FLT3LG is expressed as a noncovalentlylinked dimer by T cells and bone marrow and thymic fibroblasts. Each 36 kDa chain carries approximately 12 kDa of N- and O- linked carbohydrates. FLT3LG is structurally homologous to stem cell factor (SCF) and colony stimulating facor 1 (CSF-1). FLT3LG acts as a growth factor that increases the number of immune cells by activating the hematopoietic progenitors. It also induces the mobilization of the hematopoietic progenitors and stem cells in vivo which may help the system to kill cancer cells. FLT3LG induces the expansion of monocytes and immature dendritic cells as well as early B cell lineage differentiation. FLT3LG cooperates with IL2, IL6, IL7, and IL15 to induce NK cell development and with IL3, IL7 and IL11 to induce terminal B cell maturation. Animal studies also show FLT3LG to reduce the severity of experimentally induced allergic inflammation. FLT3LG is crucial for steady-state pDC and cDC development. A lack of FLT3L results in low levels of DCs.

Flt-3 Ligand Recombinant Protein
11-434	ProSci	0.1 mg	EUR 595.25
Description: FMS-like tyrosine kinase 3 ligand (Flt-3 Ligand) is also known as FL, Flt3L and FLT3LG, is an α-helical cytokine that promotes the differentiation of multiple hematopoietic cell lineages. FLT3LG is expressed as a noncovalentlylinked dimer by T cells and bone marrow and thymic fibroblasts. Each 36 kDa chain carries approximately 12 kDa of N- and O- linked carbohydrates. FLT3LG is structurally homologous to stem cell factor (SCF) and colony stimulating facor 1 (CSF-1). FLT3LG acts as a growth factor that increases the number of immune cells by activating the hematopoietic progenitors. It also induces the mobilization of the hematopoietic progenitors and stem cells in vivo which may help the system to kill cancer cells. FLT3LG induces the expansion of monocytes and immature dendritic cells as well as early B cell lineage differentiation. FLT3LG cooperates with IL2, IL6, IL7, and IL15 to induce NK cell development and with IL3, IL7 and IL11 to induce terminal B cell maturation. Animal studies also show FLT3LG to reduce the severity of experimentally induced allergic inflammation. FLT3LG is crucial for steady-state pDC and cDC development. A lack of FLT3L results in low levels of DCs.

Human CellExp? FLT-3 Ligand, Human Recombinant
6452-10	Biovision		EUR 321

Human CellExp? FLT-3 Ligand, Human Recombinant
6452-50	Biovision		EUR 1153

Polyclonal Goat anti-GST p-form
GST-ANTI-3	Detroit R&D	50 uL	EUR 280

Human CellExp? FLT-3 Ligand, Mouse Recombinant
P1382-10	Biovision		EUR 164

Human CellExp? FLT-3 Ligand, Mouse Recombinant
P1382-50	Biovision		EUR 479

Recombinant Mouse Flt-3 Ligand Protein
RP01058	Abclonal	10 μg	EUR 155

Flt-3 Ligand (rMuFlt-3), murine (mouse)
RC234-16	Bio Basic	1mg	EUR 3312.5

Flt-3 Ligand, His (CHO-expressed), Mouse
HY-P7354	MedChemExpress	50ug	EUR 612

Flt-3 Ligand ELISA Kit (Human) : 96 Wells (OKAG00123)
OKAG00123	Aviva Systems Biology	96 Wells	EUR 596
Description: Description of target: Dendritic cells (DCs) provide the key link between innate and adaptive immunity by recognizing pathogens and priming pathogen-specific immune responses. FLT3LG controls the development of DCs and is particularly important for plasmacytoid DCs and CD8 (see MIM 186910)-positive classical DCs and their CD103 (ITGAE; MIM 604682)-positive tissue counterparts (summary by Sathaliyawala et al., 2010 [PubMed 20933441]).[supplied by OMIM, Jan 2011];Species reactivity: Human;Application: ELISA;Assay info: Quantitative Colorimentric Sandwich ELISA;Sensitivity: 16 pg/mL

Recombinant Human sRANK Ligand Protein
PROTO14788-3	BosterBio	10ug	EUR 317
Description: RANKL and RANK are members of the TNF superfamily of ligands and receptors that play an important role in the regulation of specific immunity and bone turnover. RANK (receptor) was originally identified as a dendritic-cell-membrane protein, which by interacting with RANKL augments the ability of dendritic cells to stimulate naïve T-cell proliferation in a mixed lymphocyte reaction, to promote the survival of RANK + T cells, and to regulate T-cell-dependent immune response. RANKL, which is expressed in a variety of cells including osteoblasts, fibroblasts, activated T-cells and bone marrow stromal cells, is also capable of interacting with a decoy receptor called OPG. Binding of soluble OPG to sRANKL inhibits osteoclastogenesis by interrupting the signaling between stromal cells and osteoclastic progenitor cells, thereby leading to excess accumulation of bone and cartilage. Recombinant human sRANKL is a 20.0 kDa polypeptide comprising the TNF homologous region of RANKL (176 amino acid residues).

Recombinant Flt-3 Ligand Protein (Thr 27-Pro 185)
VAng-1572Lsx-1mg	Creative Biolabs	1 mg	EUR 7749
Description: Human Flt-3 Ligand is expressed in HEK 293 cells. (Uniprot ID: AAI26294)

Recombinant Flt-3 Ligand Protein (Thr 27-Pro 185)
VAng-1572Lsx-20g	Creative Biolabs	20 µg	EUR 594
Description: Human Flt-3 Ligand is expressed in HEK 293 cells. (Uniprot ID: AAI26294)

Recombinant Flt-3 Ligand Protein (Thr 27-Pro 185)
VAng-1572Lsx-50g	Creative Biolabs	50 µg	EUR 985
Description: Human Flt-3 Ligand is expressed in HEK 293 cells. (Uniprot ID: AAI26294)

Rabbit Polyclonal antibody Anti-CRBN
Anti-CRBN	ImmunoStep	50 µg	EUR 349

Anti-Phospho-Flt-3 (Y842) antibody
STJ90580	St John's Laboratory	200 µl	EUR 197
Description: Rabbit polyclonal to Phospho-Flt-3 (Y842).

Anti-Phospho-Flt-3 (Y969) antibody
STJ90944	St John's Laboratory	200 µl	EUR 197
Description: Rabbit polyclonal to Phospho-Flt-3 (Y969).

Human, Flt3 Ligand Human Recombinant Protein, His Tag
PROTP49771-3	BosterBio	Regular: 20ug	EUR 317
Description: Flt3-Ligand Human Recombinant produced in E.Coli is a non-glycosylated, polypeptide chain containing 165 amino acids (including his tag) and having a molecular mass of 18.9 kDa. Flt3-Ligand is purified by proprietary chromatographic techniques.

Human FMS-like tyrosine kinase 3 ligand, Flt-3L ELISA Kit
CSB-E04554h-24T	Cusabio	1 plate of 24 wells	EUR 165
Description: Quantitativesandwich ELISA kit for measuring Human FMS-like tyrosine kinase 3 ligand, Flt-3L in samples from serum, plasma, cell culture supernates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Human FMS-like tyrosine kinase 3 ligand, Flt-3L ELISA Kit
1-CSB-E04554h	Cusabio	EUR 500.00 EUR 3402.00 EUR 1820.00	1 plate of 96 wells 10 plates of 96 wells each 5 plates of 96 wells each
Description: Quantitativesandwich ELISA kit for measuring Human FMS-like tyrosine kinase 3 ligand, Flt-3L in samples from serum, plasma, cell culture supernates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Human FMS-like tyrosine kinase 3 ligand(Flt-3L)ELISA Kit
GA-E0932HM-48T	GenAsia Biotech	48T	EUR 289

Human FMS-like tyrosine kinase 3 ligand(Flt-3L)ELISA Kit
GA-E0932HM-96T	GenAsia Biotech	96T	EUR 466

Human FMS-like tyrosine kinase 3 ligand,Flt-3L ELISA Kit
201-12-0916	SunredBio	96 tests	EUR 440
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids.

Human Flt-3 Ligand Protein (Thr 27-Pro 185) [His] (HEK293)
VAng-1574Lsx-1mg	Creative Biolabs	1 mg	EUR 7749
Description: Human Flt-3 Ligand, His tag, is expressed in HEK 293 cells. (Uniprot ID: P49771-1)

Human Flt-3 Ligand Protein (Thr 27-Pro 185) [His] (HEK293)
VAng-1574Lsx-20g	Creative Biolabs	20 µg	EUR 545
Description: Human Flt-3 Ligand, His tag, is expressed in HEK 293 cells. (Uniprot ID: P49771-1)

Human Flt-3 Ligand Protein (Thr 27-Pro 185) [His] (HEK293)
VAng-1574Lsx-50g	Creative Biolabs	50 µg	EUR 1013
Description: Human Flt-3 Ligand, His tag, is expressed in HEK 293 cells. (Uniprot ID: P49771-1)

Human FMS-like tyrosine kinase 3 ligand(Flt-3L)ELISA Kit
QY-E04924	Qayee Biotechnology	96T	EUR 361

Human FMS-like tyrosine kinase 3 ligand,Flt-3L ELISA Kit
CN-04040H1	ChemNorm	96T	EUR 481

Human FMS-like tyrosine kinase 3 ligand,Flt-3L ELISA Kit
CN-04040H2	ChemNorm	48T	EUR 307

Flt-3 Antibody
abx019085-100ug	Abbexa	100 ug	EUR 342

Recombinant Flt-3 Ligand Protein (Gly 27-Arg 188) [His]
VAng-1571Lsx-100g	Creative Biolabs	100 µg	EUR 1013
Description: Mouse Flt-3 Ligand, His tag, is expressed in HEK 293 cells. (Uniprot ID: P49772-1)

Recombinant Flt-3 Ligand Protein (Gly 27-Arg 188) [His]
VAng-1571Lsx-1mg	Creative Biolabs	1 mg	EUR 6402
Description: Mouse Flt-3 Ligand, His tag, is expressed in HEK 293 cells. (Uniprot ID: P49772-1)

Anti-Flt-4 Antibody
A01276-1	BosterBio	100ul	EUR 397
Description: Rabbit Polyclonal Antibody for Flt-4 Antibody (FLT4) detection.tested for IHC, WB in Human, Mouse, Rat.

Anti-Flt-1 antibody
STJ98080	St John's Laboratory	100 µl	EUR 234
Description: Mouse monoclonal to Flt-1.

Anti-Flt-4 antibody
STJ98081	St John's Laboratory	100 µl	EUR 234
Description: Mouse monoclonal to Flt-4.

Anti-Flt-4 antibody
STJ98712	St John's Laboratory	200 µl	EUR 197
Description: Rabbit polyclonal to Flt-4.

Anti-Flt-1 antibody
STJ93093	St John's Laboratory	200 µl	EUR 197
Description: Rabbit polyclonal to Flt-1.

Anti-Flt-1 antibody
STJ93094	St John's Laboratory	200 µl	EUR 197
Description: Rabbit polyclonal to Flt-1.

Anti-Flt-4 antibody
STJ98975	St John's Laboratory	200 µl	EUR 197
Description: Rabbit polyclonal to Flt-4.

Mouse FMS-like tyrosine kinase 3 ligand, Flt-3L ELISA Kit
CSB-E04555m-24T	Cusabio	1 plate of 24 wells	EUR 165
Description: Quantitative sandwich ELISA kit for measuring Mouse FMS-like tyrosine kinase 3 ligand, Flt-3L in samples from serum, plasma, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Mouse FMS-like tyrosine kinase 3 ligand, Flt-3L ELISA Kit
1-CSB-E04555m	Cusabio	EUR 703.00 EUR 4843.00 EUR 2570.00	1 plate of 96 wells 10 plates of 96 wells each 5 plates of 96 wells each
Description: Quantitative sandwich ELISA kit for measuring Mouse FMS-like tyrosine kinase 3 ligand, Flt-3L in samples from serum, plasma, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Rat FMS-like tyrosine kinase 3 ligand, Flt-3L ELISA Kit
CSB-E07336r-24T	Cusabio	1 plate of 24 wells	EUR 165
Description: Quantitativesandwich ELISA kit for measuring Rat FMS-like tyrosine kinase 3 ligand, Flt-3L in samples from serum, plasma, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Rat FMS-like tyrosine kinase 3 ligand, Flt-3L ELISA Kit
1-CSB-E07336r	Cusabio	EUR 723.00 EUR 4883.00 EUR 2591.00	1 plate of 96 wells 10 plates of 96 wells each 5 plates of 96 wells each
Description: Quantitativesandwich ELISA kit for measuring Rat FMS-like tyrosine kinase 3 ligand, Flt-3L in samples from serum, plasma, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Mouse FMS-like tyrosine kinase 3 ligand(Flt-3L)ELISA Kit
GA-E0086MS-48T	GenAsia Biotech	48T	EUR 336

Mouse FMS-like tyrosine kinase 3 ligand(Flt-3L)ELISA Kit
GA-E0086MS-96T	GenAsia Biotech	96T	EUR 534

Rat FMS-like tyrosine kinase 3 ligand(Flt-3L)ELISA Kit
GA-E0069RT-48T	GenAsia Biotech	48T	EUR 317

Rat FMS-like tyrosine kinase 3 ligand(Flt-3L)ELISA Kit
GA-E0069RT-96T	GenAsia Biotech	96T	EUR 496

Rat FMS-like tyrosine kinase 3 ligand(Flt-3L)ELISA Kit
QY-E11584	Qayee Biotechnology	96T	EUR 361

Mouse FMS-like tyrosine kinase 3 ligand(Flt-3L)ELISA Kit
QY-E20599	Qayee Biotechnology	96T	EUR 361

Rat FMS-like tyrosine kinase 3 ligand,Flt-3L ELISA Kit
CN-01951R1	ChemNorm	96T	EUR 478

Rat FMS-like tyrosine kinase 3 ligand,Flt-3L ELISA Kit
CN-01951R2	ChemNorm	48T	EUR 329

Mouse FMS-like tyrosine kinase 3 ligand,Flt-3L ELISA Kit
CN-02472M1	ChemNorm	96T	EUR 467

Mouse FMS-like tyrosine kinase 3 ligand,Flt-3L ELISA Kit
CN-02472M2	ChemNorm	48T	EUR 316

Human Flt-3 Ligand Protein (Thr 27-Pro 185) [His] (Baculovirus-Insect Cells)
VAng-1573Lsx-100g	Creative Biolabs	100 µg	EUR 1013
Description: Human Flt-3 Ligand, His tag, is expressed in Baculovirus-Insect cells. (Uniprot ID: P49771-1)

Human Flt-3 Ligand Protein (Thr 27-Pro 185) [His] (Baculovirus-Insect Cells)
VAng-1573Lsx-1mg	Creative Biolabs	1 mg	EUR 6402
Description: Human Flt-3 Ligand, His tag, is expressed in Baculovirus-Insect cells. (Uniprot ID: P49771-1)

Anti-VEGF Receptor 3/FLT4 Antibody
A01276-3	BosterBio	100ug/vial	EUR 334

Anti-14-3-3 alpha + beta Rabbit Monoclonal Antibody
M02431-3	BosterBio	100ug/vial	EUR 397
Description: Rabbit Monoclonal 14-3-3 alpha + beta Antibody. Validated in Flow Cytometry, IP, IF, IHC, ICC, WB and tested in Human, Mouse, Rat.

Polyclonal Goat anti-GST α-form
GST-ANTI-1	Detroit R&D	50 uL	EUR 280

Polyclonal Goat anti-GST μ-form
GST-ANTI-2	Detroit R&D	50 uL	EUR 280

Anti-active Caspase-3 Rabbit Monoclonal Antibody
M00334-3	BosterBio	100ug/vial	EUR 397
Description: Anti-active Caspase-3 Rabbit Monoclonal Antibody tested for IF, IHC, ICC, WB in Human

Anti-Galectin 3/LGALS3 Antibody (monoclonal, 12B12)
M00621-3	BosterBio	100ug/vial	EUR 334

Anti-Human Ki67 Antibody
M00254-3	BosterBio	100ul	EUR 397
Description: Rabbit Polyclonal Human Ki67 Antibody. Validated in IHC, WB and tested in Human, Mouse, Rat.

Anti-Human IBA1 Antibody
M01394-3	BosterBio	100ul	EUR 397
Description: Chicken Polyclonal Human IBA1 Antibody. Validated in IF, IHC, WB and tested in Human.

Anti-Phospho-Flt-1 (Y1048) antibody
STJ91223	St John's Laboratory	200 µl	EUR 197
Description: Rabbit polyclonal to Phospho-Flt-1 (Y1048).

Anti-Phospho-Flt-1 (Y1213) antibody
STJ91359	St John's Laboratory	200 µl	EUR 197
Description: Rabbit polyclonal to Phospho-Flt-1 (Y1213).

Anti-Flk-1/Flt-4 antibody
STJ93091	St John's Laboratory	200 µl	EUR 197
Description: Rabbit polyclonal to Flk-1/Flt-4.

Anti-Phospho-Flt-1 (Y1333) antibody
STJ90838	St John's Laboratory	200 µl	EUR 197
Description: Rabbit polyclonal to Phospho-Flt-1 (Y1333).

anti- VEGFR-1/FLT-1 antibody
FNab09393	FN Test	100µg	EUR 505.25
Description: Antibody raised against VEGFR-1/FLT-1

Anti-VEGFR-1/FLT-1 antibody
PAab09393	Lifescience Market	100 ug	EUR 355

Flt-3L/ Rat Flt- 3L ELISA Kit
ELA-E0038r	Lifescience Market	96 Tests	EUR 886

Anti-Glyceraldehyde 3-Phosphate Dehydrogenase [GAPDH] Monoclonal Antibody
M00227-3	BosterBio	100ul	EUR 397
Description: Mouse Monoclonal Glyceraldehyde 3-Phosphate Dehydrogenase [GAPDH] Antibody. Validated in IHC, WB and tested in Equine.

Rabbit Anti-Human FLT-4/VEGFR-3 IgG #2, aff pure
FLT42-A	Alpha Diagnostics	100 ug	EUR 482

anti-Fas Ligand
YF-PA10286	Abfrontier	50 ul	EUR 363
Description: Mouse polyclonal to Fas Ligand

anti-Fas Ligand
YF-PA10287	Abfrontier	100 ul	EUR 403
Description: Rabbit polyclonal to Fas Ligand

anti-Fas Ligand
YF-PA10288	Abfrontier	100 ug	EUR 403
Description: Rabbit polyclonal to Fas Ligand

anti-Flt3 ligand
YF-PA11819	Abfrontier	50 ul	EUR 363
Description: Mouse polyclonal to Flt3 ligand

anti-Flt3 ligand
YF-PA11820	Abfrontier	50 ug	EUR 363
Description: Mouse polyclonal to Flt3 ligand

anti-Flt3 ligand
YF-PA11821	Abfrontier	100 ug	EUR 403
Description: Rabbit polyclonal to Flt3 ligand

anti-Fas Ligand
YF-PA23235	Abfrontier	50 ul	EUR 334
Description: Mouse polyclonal to Fas Ligand

anti-Fas Ligand
YF-PA23236	Abfrontier	50 ul	EUR 334
Description: Mouse polyclonal to Fas Ligand

anti-Flt3 ligand
YF-PA23726	Abfrontier	50 ul	EUR 334
Description: Mouse polyclonal to Flt3 ligand

Flt-3 (phospho Tyr842) Polyclonal Antibody
ABP54322-003ml	Abbkine	0.03ml	EUR 158
Description: A polyclonal antibody for detection of Flt-3 phospho Tyr842) from Human, Mouse. This Flt-3 phospho Tyr842) antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human Flt-3 around the phosphorylation site of Y842

Flt-3 (phospho Tyr842) Polyclonal Antibody
ABP54322-01ml	Abbkine	0.1ml	EUR 289
Description: A polyclonal antibody for detection of Flt-3 phospho Tyr842) from Human, Mouse. This Flt-3 phospho Tyr842) antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human Flt-3 around the phosphorylation site of Y842

Flt-3 (phospho Tyr842) Polyclonal Antibody
ABP54322-02ml	Abbkine	0.2ml	EUR 414
Description: A polyclonal antibody for detection of Flt-3 phospho Tyr842) from Human, Mouse. This Flt-3 phospho Tyr842) antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human Flt-3 around the phosphorylation site of Y842

Flt-3 (phospho Tyr969) Polyclonal Antibody
ABP54323-003ml	Abbkine	0.03ml	EUR 158
Description: A polyclonal antibody for detection of Flt-3 phospho Tyr969) from Human. This Flt-3 phospho Tyr969) antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human Flt-3 around the phosphorylation site of Y969

Flt-3 (phospho Tyr969) Polyclonal Antibody
ABP54323-01ml	Abbkine	0.1ml	EUR 289
Description: A polyclonal antibody for detection of Flt-3 phospho Tyr969) from Human. This Flt-3 phospho Tyr969) antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human Flt-3 around the phosphorylation site of Y969

Flt-3 (phospho Tyr969) Polyclonal Antibody
ABP54323-02ml	Abbkine	0.2ml	EUR 414
Description: A polyclonal antibody for detection of Flt-3 phospho Tyr969) from Human. This Flt-3 phospho Tyr969) antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human Flt-3 around the phosphorylation site of Y969

Flt-3 / Flk-2 Recombinant Protein
11-284	ProSci	0.1 mg	EUR 595.25
Description: Flt-3(Receptor-type tyrosine-protein kinase FLT3) is also known as FLK-2(Fetal liver kinase-2), STK-1(Stem cell tyrosine kinase 1), CD135. FLT3 is a cytokine receptor which belongs to the receptor tyrosine kinase class III. Tyrosine-protein kinase that acts as cell-surface receptor for the cytokine FLT3LG and regulates differentiation, proliferation and survival of hematopoietic progenitor cells and of dendritic cells. Promotes phosphorylation of SHC1 and AKT1, and activation of the downstream effector MTOR. Promotes activation of RAS signaling and phosphorylation of downstream kinases, including MAPK1/ERK2 and/or MAPK3/ERK1. Mutations that cause constitutive kinase activity promote cell proliferation and resistance to apoptosis via the activation of multiple signaling pathways.

Flt-3 / Flk-2 Recombinant Protein
11-343	ProSci	0.1 mg	EUR 542.75
Description: Flt-3(Receptor-type tyrosine-protein kinase FLT3) is also known as FLK-2(Fetal liver kinase-2), STK-1(Stem cell tyrosine kinase 1), CD135. FLT3 is a cytokine receptor which belongs to the receptor tyrosine kinase class III. Tyrosine-protein kinase that acts as cell-surface receptor for the cytokine FLT3LG and regulates differentiation, proliferation and survival of hematopoietic progenitor cells and of dendritic cells. Promotes phosphorylation of SHC1 and AKT1, and activation of the downstream effector MTOR. Promotes activation of RAS signaling and phosphorylation of downstream kinases, including MAPK1/ERK2 and/or MAPK3/ERK1. Mutations that cause constitutive kinase activity promote cell proliferation and resistance to apoptosis via the activation of multiple signaling pathways.

Anti-MRP1 (human) Monoclonal Antibody (QCRL-1)
M00872-3	BosterBio	1ml	EUR 675
Description: Mouse Monoclonal MRP1 (human) Antibody (QCRL-1). Validated in IP, IF and tested in Human.

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Silencing of LINC00324 or FasL suppressed expression of stemness-related genes, cell viability, proliferation, migration, invasion, self-renewal, and tumorigenesis, however enhanced cell apoptosis. Taken collectively, LINC00324 promotes the expression of FasL by means of the recruitment of PU.1, which in the end maintains the organic properties of LCSCs, thus, highlighting LINC00324 as a promising therapeutic candidate for HCC.