Human intrahepatic regulatory T cells are functional, require IL-2 from effector cells for survival, and are susceptible to Fas ligand-mediated apoptosis.

Regulatory T cells (Treg ) suppress T effector cell proliferation and preserve immune homeostasis. Autoimmune liver illnesses persist regardless of excessive frequencies of Treg within the liver, suggesting that the native hepatic microenvironment may have an effect on Treg stability, survival, and performance. We hypothesized that interactions between Treg and endothelial cells throughout recruitment after

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